Gunnar Kvalheim Selected Research

Neoplasms (Cancer)

5/2024	CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia.
4/2024	Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16.
4/2024	Transient TCR-based T-cell therapy in a patient with advanced treatment-resistant MSI-high colorectal cancer.
7/2023	A phase I prospective, non-randomized trial of autologous dendritic cell-based cryoimmunotherapy in patients with metastatic castration-resistant prostate cancer.
1/2023	ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma.
1/2022	A phase I/II escalation trial design T-RAD: Treatment of metastatic lung cancer with mRNA-engineered T cells expressing a T cell receptor targeting human telomerase reverse transcriptase (hTERT).
1/2021	Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy.
1/2021	Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors.
2/2019	NK cells specifically TCR-dressed to kill cancer cells.
1/2019	Combining the oncolytic peptide LTX-315 with doxorubicin demonstrates therapeutic potential in a triple-negative breast cancer model.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Gunnar Kvalheim Research Topics

Disease

38	Neoplasms (Cancer) 05/2024 - 11/2004
11	Prostatic Neoplasms (Prostate Cancer) 07/2023 - 01/2003
8	Melanoma (Melanoma, Malignant) 01/2021 - 06/2005
6	Lymphoma (Lymphomas) 05/2024 - 11/2004
5	Breast Neoplasms (Breast Cancer) 08/2012 - 11/2004
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 05/2024 - 10/2014
3	Colorectal Neoplasms (Colorectal Cancer) 04/2024 - 01/2017
3	Neoplasm Metastasis (Metastasis) 04/2024 - 01/2003
3	Leukemia 01/2023 - 07/2007
3	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021 - 06/2011
3	Infections 01/2021 - 01/2011
3	Hypersensitivity (Allergy) 01/2016 - 01/2011
2	Microsatellite Instability 04/2024 - 01/2017
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 12/2006
2	Lung Neoplasms (Lung Cancer) 01/2022 - 01/2013
2	Carcinoma (Carcinomatosis) 04/2020 - 04/2005
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2019 - 11/2003
2	Hypoxia (Hypoxemia) 01/2017 - 01/2011
2	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2015 - 03/2011
2	Graft vs Host Disease (Graft-Versus-Host Disease) 09/2014 - 01/2011
1	Ascites 01/2021
1	B-Cell Leukemia (Leukemia, B Cell) 01/2021
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2019
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2019
1	Triple Negative Breast Neoplasms 01/2019
1	Colonic Neoplasms (Colon Cancer) 01/2017
1	Fibrosarcoma 01/2017
1	Sarcoma (Soft Tissue Sarcoma) 01/2017
1	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 01/2017
1	Stomach Neoplasms (Stomach Cancer) 01/2017
1	Residual Neoplasm 10/2014
1	Wilms Tumor (Wilm's Tumor) 10/2014
1	Glioblastoma (Glioblastoma Multiforme) 09/2013
1	Brain Neoplasms (Brain Tumor) 09/2013
1	Nervous System Diseases (Neurological Disorders) 05/2013

Drug/Important Bio-Agent (IBA)

12	AntigensIBA 04/2024 - 06/2005
12	Messenger RNA (mRNA)IBA 04/2024 - 04/2005
9	CytokinesIBA 05/2024 - 05/2007
9	VaccinesIBA 01/2023 - 06/2005
8	Peptides (Polypeptides)IBA 01/2021 - 12/2006
6	Proteins (Proteins, Gene)FDA Link 01/2023 - 04/2005
5	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2022 - 12/2006
4	Chimeric Antigen ReceptorsIBA 05/2024 - 05/2011
4	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2022 - 01/2017
3	RNA (Ribonucleic Acid)IBA 01/2023 - 06/2005
3	Mitochondrial DNA (mtDNA)IBA 08/2017 - 08/2013
2	CD19 AntigensIBA 01/2021 - 01/2019
2	LTX-315IBA 01/2019 - 01/2017
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017 - 11/2005
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2017 - 11/2005
2	Interleukin-8 (Interleukin 8)IBA 01/2017 - 11/2005
2	EpitopesIBA 01/2016 - 06/2011
2	SurvivinIBA 01/2016 - 07/2013
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2015 - 12/2006
2	Rituximab (Mabthera)FDA Link 01/2015 - 03/2011
2	Cancer VaccinesIBA 07/2013 - 06/2005
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 08/2012 - 11/2004
1	Biomarkers (Surrogate Marker)IBA 04/2024
1	Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA 04/2024
1	Tumor Biomarkers (Tumor Markers)IBA 04/2024
1	Immunotoxins (Immunotoxin)IBA 04/2020
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 04/2020
1	Epithelial Cell Adhesion MoleculeIBA 04/2020
1	SolutionsIBA 02/2019
1	invariant chain (Ii-Key)IBA 01/2019
1	AlarminsIBA 01/2019
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 11/2017
1	alvocidib (flavopiridol)IBA 11/2017
1	Ethidium (Ethidium Bromide)IBA 08/2017
1	AutoantigensIBA 01/2017
1	Antigen Receptors (Antigen Receptor)IBA 01/2017
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2017
1	Differentiation AntigensIBA 01/2017
1	Conditioned Culture MediaIBA 01/2017
1	Streptozocin (Streptozotocin)FDA Link 01/2017
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2017
1	Adenine FDA LinkGeneric 01/2017
1	IpilimumabIBA 01/2016
1	InterleukinsIBA 12/2015
1	Interleukin-3 (Interleukin 3)IBA 12/2015
1	CarcinogensIBA 12/2015
1	SuspensionsIBA 09/2013
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 07/2013
1	AntibodiesIBA 06/2013
1	Histone Deacetylases (Histone Deacetylase)IBA 05/2013

Therapy/Procedure

13	Therapeutics 04/2024 - 01/2003
13	Immunotherapy 07/2023 - 06/2011
7	Drug Therapy (Chemotherapy) 01/2019 - 11/2004
4	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2021 - 01/2016
4	Radiotherapy 01/2015 - 11/2005
2	Injections 01/2015 - 11/2004
2	Stem Cell Transplantation 01/2011 - 11/2003
1	Cryosurgery 07/2023
1	Castration 07/2023
1	Induction Chemotherapy 01/2023
1	Hematopoietic Stem Cell Transplantation 01/2023
1	Prostatectomy (Retropubic Prostatectomy) 01/2022
1	Surgical Instruments (Clip) 01/2019
1	Transplantation 09/2014